SilcsBio’s parent company, Early Charm, has a job opening to work with SilcsBio and other portfolio companies focused on Drug Design and Machine Vision.


Immediate Job Opening


Machine Learning

Deep Tech Applications


July 27, 2021


What we do:

Early Charm creates, owns, and operates businesses that convert science into revenue.

We are the management team, the operators, and the entrepreneurs. We do not write checks and just pop in for board meetings. We show up to our labs, our production facilities, and our offices every day to do all the heavy lifting in our portfolio companies.

Our scientists and engineers work across our entire portfolio, never just one venture. This brings extraordinary expertise to the earliest stages of product development. The lack of silos fosters creativity and attracts the most collaborative people.

Similarly, our sales & marketing team works across our portfolio enabling us to have the voice of customers heard early and often as we consider product development. Add in our experts in law, intellectual property, accounting, finance, licensing, purchasing and more to get the complete team to build our businesses.


What you will do:

You will work primarily with our companies selling computational drug design software. Our companies have well developed, scientifically validated algorithms that model proteins in complex virtual environments. Our customers use these models to design molecules that efficiently and selectively interact with the proteins. Interfering with the actions of proteins is the most common way that therapeutic drugs function.

We have an exceptional team of computational chemists and a recurring customer base. Our technology is currently based on producing large amounts of data from physics-based simulations and wet lab testing. You will marry this data with machine learning to predict molecular properties to create breakthroughs in drug discovery.

While the immediate need is for your help with our computational drug design companies, you will also have opportunities to work with our machine vision companies to engage in the development of our algorithm demos and facilitate productization. We are using machine vision in areas such as determining biomass on shrimp farms, making decisions on the viability of kidneys for transplant, detecting defects in automotive coatings, and fall detection.


What you need to be successful:

You will really need to have a track record of successes using machine learning especially with 3D grids and graph-based neural networks. A basic understanding of chemistry and physics is needed with advanced knowledge of the fields typically found in advanced degree programs being even better.


What we will do for you:

Career development is our top priority for you. While we love the idea of people joining Early Charm forever, we are realistic to understand that we may be a steppingstone to other opportunities or a way for you to explore career options. Regardless of your reasons for joining us, our commitment is to help you.


Where you will work:

We are at the center of the entrepreneurial renaissance of Baltimore giving you the opportunity to interact with some of the nation’s most exciting technology companies. Located at 1100 Wicomico Street, our labs, production space and offices are intermingled with firms doing engineering design, software development, specialty textiles, 3D printing, and so much more. There is even a brewery.

Early Charm is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.


Please send your resume and cover letter to