SILCS Application Studies

Acyl-2-aminobenzimidazoles: A novel class of neuroprotective agents targeting mGluR5

June 1, 2018

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Cyclopropyl-containing positive allosteric modulators of metabotropic glutamate receptor subtype 5

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Iminoguanidines as Allosteric Inhibitors of the Iron-Regulated Heme Oxygenase (HemO) of Pseudomonas aeruginosa

September 21, 2017

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Ribosome-templated azide−alkyne cycloadditions: synthesis of potent macrolide antibiotics by in situ click chemistry

April 20, 2016

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Structure-Based Design of N-Substituted 1-Hydroxy-4-sulfamoyl-2-naphthoates as Selective Inhibitors of the Mcl-1 Oncoprotein

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The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with Bak, Molecular Cell

September 17, 2015

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