Beyond Binding – Fast, Scalable koff Predictions Powered by SILCS and AI SilcsBio hosted a webinar on January 15th, 2026 showcasing how SILCS‑Kinetics is transforming the study of ligand binding–unbinding kinetics by enabling rapid, scalable predictions of ligand dissociation rates (koff) using a combination of physics‑based modeling and machine learning.   About SILCS‑Kinetics Understanding ligand [...]

Sign up here! CADD in an industrial setting requires high accuracy with maximum throughput to drive the drug discovery process. The SILCS technology, in conjunction with the CGenFF program, attains this at an unprecedented level through the use of pre-computed FragMaps that can be used throughout the drug discovery and optimization process. [...]