THE SILCSBIO DIFFERENCE
SILCS
Site-Identification by Ligand Competitive Saturation
Our proprietary CADD software technology, SILCS, generates highly accurate 3D free energy maps called “FragMaps” which account for conformational nuances to reveal hidden pockets of opportunity.
SILCS FragMaps technology gives you an intuitive way of interacting with and visualizing the entire protein surface, further enabling your drug discovery team to:
- Accelerate drug discovery timelines
- Enhance high throughput screening to drive hit selection
- Reduce drug development costs
- Bolster drug development pipelines
SILCS
Site-Identification by Ligand Competitive Saturation
Our proprietary CADD software technology, SILCS, generates highly accurate 3D free energy maps called “FragMaps” which account for conformational nuances to reveal hidden pockets of opportunity.
SILCS FragMaps technology gives you an intuitive way of interacting with and visualizing the entire protein surface, further enabling your drug discovery team to:
- Accelerate drug discovery timelines
- Enhance high throughput screening to drive hit selection
- Reduce drug development costs
- Bolster drug development pipelines
WHY SILCSBIO OUTPERFORMS ALL OTHERS
SILCS is built on rigorous free energy calculations employing:
- Multiple small molecule probes with diverse functional groups
- Explicit solvent modeling
- Target molecule flexibility
- Advanced sampling methods (GCMC/MD) to identify cryptic pockets
WHY SILCSBIO OUTPERFORMS ALL OTHERS
SILCS is built on rigorous free energy calculations employing:
- Multiple small molecule probes with diverse functional groups
- Explicit solvent modeling
- Target molecule flexibility
- Advanced sampling methods (GCMC/MD) to identify cryptic pockets
OUR TEAM
Our team is committed to delivering the fastest, most reliable drug designs for your highest value drug programs. We are committed to providing our expertise and technology to unlock a whole new world of possibilities for you and your team.
OUR PARTNERS AND COLLABORATORS
Job Opening: Scientist – Medicinal Chemistry
Position: Scientist – Medicinal Chemistry What we do: At SilcsBio, we are passionate about accelerating the pace of drug discovery. We are scientists, chemists, programmers, and innovators developing and utilizing next generation computer-aided drug design for end-to-end solutions in small molecule and biologics development. We are seeking a Medicinal Chemistry [...]
Job Opening: Scientist – Medicinal Chemistry and Computational Design
Position: Scientist – Medicinal Chemistry and Computational Design What we do: Early Charm creates, owns, and operates businesses that convert science into revenue. We are the management team, the operators, and the entrepreneurs. We do not write checks and just pop in for board meetings. We show up to our [...]
SilcsBio and Helix BioStructures Launch Partnership to Collaborate in Fueling Pharmaceutical Drug Design Opportunities
SilcsBio and Helix BioStructures to tap mutual areas of expertise in drug design to spur new drug design opportunities for pharmaceutical and research organizations August 29, 2022, Baltimore, MD and Indianapolis, IN – SilcsBio, a technology company that develops and markets software and services for structure-based drug design, today announced [...]
