THE SILCSBIO DIFFERENCE

SILCS
Site Identification by Ligand Competitive Saturation

Our proprietary CADD software technology, SILCS, generates highly accurate 3D free energy maps called “FragMaps”, which account for conformational nuances, to reveal hidden pockets of opportunity.
SILCS FragMaps technology gives you an intuitive way of interacting with and visualizing the entire protein surface, further enabling your drug discovery team to:
- Accelerate drug discovery timelines
- Enhance high-throughput screening to drive hit selection
- Reduce drug development costs
- Bolster drug development pipelines
SILCS
Site Identification by Ligand Competitive Saturation
Our proprietary CADD software technology, SILCS, generates highly accurate 3D free energy maps called “FragMaps”, which account for conformational nuances, to reveal hidden pockets of opportunity.
SILCS FragMaps technology gives you an intuitive way of interacting with and visualizing the entire protein surface, further enabling your drug discovery team to:
- Accelerate drug discovery timelines
- Enhance high-throughput screening to drive hit selection
- Reduce drug development costs
- Bolster drug development pipelines
WHY SILCSBIO OUTPERFORMS ALL OTHERS
SILCS is built on rigorous free energy calculations employing:
- Multiple small molecule probes with diverse functional groups
- Explicit solvent modeling
- Target molecule flexibility
- Advanced sampling methods (GCMC/MD) to identify cryptic pockets
WHY SILCSBIO OUTPERFORMS ALL OTHERS
SILCS is built on rigorous free energy calculations employing:
- Multiple small molecule probes with diverse functional groups
- Explicit solvent modeling
- Target molecule flexibility
- Advanced sampling methods (GCMC/MD) to identify cryptic pockets

OUR TEAM
Our team is committed to delivering the fastest, most reliable solutions for your highest value drug programs. Take advantage of our expertise and technology to unlock new possibilities for your design team.

OUR PARTNERS AND COLLABORATORS





