Visualize Drug Design in a Whole New Way

Visualize Drug Design in a Whole New Way

SilcsBio provides computer-aided drug design solutions that dramatically accelerate and improve small molecule and biologic drug discovery pipelines.

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SilcsBio Response to Covid-19

SilcsBio Response to Covid-19

SilcsBio has created a FragMap library of many of the proteins of the Covid-19 virus to drive your drug discovery efforts.

Covid-19 Main Protease FragMap
SILCS FragMap

SILCS

Site-Identification by Ligand Competitive Saturation

Our proprietary CADD software technology, SILCS, generates highly accurate 3D free energy maps called “FragMaps” which account for conformational nuances to reveal hidden pockets of opportunity.

SILCS FragMaps technology gives you an intuitive way of interacting with and visualizing the entire protein surface, further enabling your drug discovery team to:

  • Accelerate drug discovery timelines
  • Enhance high throughput screening to drive hit selection
  • Reduce drug development costs
  • Bolster drug development pipelines
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SILCS FragMap

Why SilcsBio outperforms all others

SILCS is built on rigorous free energy calculations employing:

  • Multiple small molecule probes with diverse functional groups
  • Explicit solvent modeling
  • Target molecule flexibility
  • Advanced sampling methods (GCMC/MD) to identify cryptic pockets

The proof is in the details

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Our Team

SilcsBio provides software and services for unlocking the full potential of computer driven drug design. Our algorithms for mapping proteins will provide you with a level of detail you have never before experienced. From our highly accurate free energy maps to conformational nuances revealing hidden pockets of opportunity, you will discover a whole new world of possibilities.

Meet Our Team