THE SILCSBIO DIFFERENCE

SERVICES

Our experts provide consultation and training, paired with guided deployment of the SILCS platform technology, to enable drug discovery teams to work faster and more productively.

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SOFTWARE

Patented SILCS technology works in tandem with SILCS-Biologics, CGenFF, and SSFEP for targeted solutions or complete end-to-end drug design workflow — from hit identification to lead optimization.

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PLATFORM

Our proprietary CADD software technology, SILCS, allows researchers to visualize and interact with 3D maps of protein surfaces for drug design.

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SILCS

Site-Identification by Ligand Competitive Saturation

Our proprietary CADD software technology, SILCS, generates highly accurate 3D free energy maps called “FragMaps” which account for conformational nuances to reveal hidden pockets of opportunity.

SILCS FragMaps technology gives you an intuitive way of interacting with and visualizing the entire protein surface, further enabling your drug discovery team to:

  • Accelerate drug discovery timelines
  • Enhance high throughput screening to drive hit selection
  • Reduce drug development costs
  • Bolster drug development pipelines
View Demo

SILCS

Site-Identification by Ligand Competitive Saturation

Our proprietary CADD software technology, SILCS, generates highly accurate 3D free energy maps called “FragMaps” which account for conformational nuances to reveal hidden pockets of opportunity.

SILCS FragMaps technology gives you an intuitive way of interacting with and visualizing the entire protein surface, further enabling your drug discovery team to:

  • Accelerate drug discovery timelines
  • Enhance high throughput screening to drive hit selection
  • Reduce drug development costs
  • Bolster drug development pipelines
View Demo

WHY SILCSBIO OUTPERFORMS ALL OTHERS

SILCS is built on rigorous free energy calculations employing:

  • Multiple small molecule probes with diverse functional groups
  • Explicit solvent modeling
  • Target molecule flexibility
  • Advanced sampling methods (GCMC/MD) to identify cryptic pockets

THE PROOF IS IN THE DETAILS
Publications

WHY SILCSBIO OUTPERFORMS ALL OTHERS

SILCS is built on rigorous free energy calculations employing:

  • Multiple small molecule probes with diverse functional groups
  • Explicit solvent modeling
  • Target molecule flexibility
  • Advanced sampling methods (GCMC/MD) to identify cryptic pockets
THE PROOF IS IN THE DETAILS
Publications

OUR TEAM

Our team is committed to delivering the fastest, most reliable drug designs for your highest value drug programs. We are committed to providing our expertise and technology to unlock a whole new world of possibilities for you and your team.

Meet Our Team

OUR TEAM

Our team is committed to delivering the fastest, most reliable drug designs for your highest value drug programs. We are committed to providing our expertise and technology to unlock a whole new world of possibilities for you and your team.

Meet Our Team

OUR PARTNERS AND COLLABORATORS