The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with Bak, Molecular Cell Posted on September 17, 2015 by adamh
Site-Identification by Ligand Competitive Saturation (SILCS) assisted pharmacophore modeling, Journal of Computer Aided Molecular Design Posted on September 17, 2015 by adamh
Reproducing Crystal Binding Modes of Ligand Functional Groups using Site-Identification by Ligand Competitive Saturation (SILCS) Simulations, Journal of Chemical Information and Modeling Posted on September 17, 2015 by adamh
Computational Fragment-Based Binding Site Identification by Ligand Competitive Saturation, PLoS Computational Biology Posted on September 12, 2015September 17, 2015 by adamh
