SilcsBio Patent

SilcsBio has exclusive rights to use U.S. and foreign patents pending by the University of Maryland, Baltimore. Patents include: U.S. Patent Application 13/265,568, titled “Method for binding site identification by molecular dynamics simulation (SILCS: Site Identification by Ligand Competitive Saturation),” published as US 2012/0053067.

SILCS Drug Design Method

SILCS: Site Identification by Ligand Competitive Saturation is a ligand or drug design program that calculates the probability that general classes or specific R-groups will bind to a target molecule. This allows a medicinal chemist to design molecules that have a higher probability of binding the target protein. This method was developed by Dr. Alex MacKerell, Professor and Director of the Computer Aided Drug Design center at the University of Maryland, School of Pharmacy.